Ineluctable

(adj.) not to be avoided, changed, or resisted; inevitable

Examples:

1. June sold her Florida beach house when she heard that most geologists agree that the demise of cities near the coasts of the Atlantic Ocean is ineluctable as waters continue to rise.

2. After seeing multiple doctors who all told her to remove the tumor in her hand, June faced the ineluctable reality that she would have to have surgery.